Browsing by Keywords "Molecular docking"
Now showing items 1-4 of 4
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Development of machine learning models to predict the activity of chemical compounds against the obesity-associated melanocortin-4 receptor
(Πανεπιστήμιο Δυτικής Αττικής, 2024-10-01)Monogenic obesity caused by mutations in the Melanocortin-4 Receptor (MC4R) gene remains a significant health challenge, despite numerous efforts to find effective treatments. The MC4R is a promising target for drug ... -
Study of the orphan GPR21 towards therapeutics for metabolic disorders
(Πανεπιστήμιο Δυτικής Αττικής, 2024-10-11)Since G-Protein Coupled Receptors (GPCRs) are engaged in a variety of signal transduction pathways in many pathophysiological situations, they are important targets for the development of novel drugs. GPR21 is a ... -
Usage of machine learning and computational chemistry methodologies to predict the activity of potential antiviral compounds against the Zika virus protease
(Πανεπιστήμιο Δυτικής Αττικής, 2024-10-11)Zika virus is an arbovirus, it is transmitted through blood-feeding arthropods and can cause symptoms ranging from fever and malaise to more severe neurological and immunological complications. Despite the extensive ... -
Υπολογιστικές τεχνικές για την αναζήτηση νέων ενώσεων αναστολέων της ενζυμικής αμαύρωσης
(Πανεπιστήμιο Δυτικής Αττικής, 2023-07-14)Τις τελευταίες δεκαετίες έχει αναπτυχθεί ραγδαία η αγορά φρούτων και λαχανικών λόγω της αλλαγής των διατροφικών συνηθειών των καταναλωτών, οι οποίοι υιοθετούν πιο υγιή πρότυπα. Τα φρούτα και τα λαχανικά είναι σημαντικά ...