Bone tissue engineering & regenerative medicine

Abstract

Tissue Engineering comprises an interdisciplinary field that combines the principles of engineering and life sciences to develop biological substitutes that maintain, restore, and improve tissue function. The fundamentals of tissue engineering involve a reliable cell source, proper 3D constructs for tissue growth and support and various biomolecules that accelerate the whole procedure. This field possesses an alternative approach that overcome limitations of current organ transplantation procedures. In this direction, Bone Tissue Engineering holds prominent role as overcomes limitations of conventional clinical treatments such tissue morbidity, immune rejection, and pathogen transfer. The scope of this thesis is to discuss the fundamentals of bone tissue engineering field and analyze early and current approaches of this field.